Sertraline Induces Toxicity and Behavioral Alterations in Planarians

Figure 4

Quantification of planarian seizure-like activity evoked by sertraline. The effect of different sertraline concentrations on the seizure-like activity (pSLA) was quantified following sequential incubations of 25 min (a), 24 h (b), and 24 h after sertraline withdrawal (c). Data are expressed as mean ± SEM from 5 independent experiments (). The asterisks mean being significantly different from the other groups: , , and (ns means not significant).

(a)

(b)

(c)