Decreased Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutation

Figure 5

Comparison of the wild type and mutant COMP proteins. (a) Structural superimposition of the wild type COMP (yellow) and mutant COMP (cyan): purple in the -strand showed the mutation site and it is amplified in (b) wild type and (c) mutant type. The changed secondary structures were amplified in (d), (e), and (f), respectively.