Research Article

Decreased Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutation

Table 1

Plasma levels of COMP and CTX-II in the affected individuals and age-matched controls.

GroupAge rangeCOMP (ng/ml)CTX-II (pg/ml)
Mean ± SDMean ± SD

PSACH335–650.0000.000
Control934–64
PC12.50.8640.497
Control32-3

Plasma levels of COMP were significantly higher in the adult control than in the controls less than three years of age, . Plasma levels of CTX-II were not different between the adult controls and the controls less than three years of age, . PC: presymptomatic carrier.