Review Article

Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems

Table 2

Liposomes used as EGCG carriers. Note. N/A denotes “not available” data.

ParticleLoading capacity
(%)
Loading efficiency
(%)
Size (nm)Administration route In vitro/in vivo resultsRef.

Egg lecithin and cholesterolN/A45–7889–93TopicalEnhanced anti-MRSA activity in vitro and in vivo[33]

PhC and cholesterolN/A85.8 ± 1.65180OralFavorable release profile in the gastrointestinal fluids.[34]

Sorbitan monostearate and cholesterolN/A40100OralThe nanoformulation presents a high stability in neutral pH and enhances the cellular permeability in caco-2 cell monolayer.[35]

Cholesterol, phosphatidylcholine, and Tween-8060.21 ± 1.59N/A126.7 ± 4.3N/AEnhancing synergistic effects between EGCG and paclitaxel in inducing apoptosis in MDA-MB-231 breast cancer cells.[36]