Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems

Table 4

Gold nanoparticles used as EGCG carriers. Note. N/A denotes “not available” data.

Particle	Loading capacity (%)	Loading efficiency (%)	Size (nm)	Administration route	In vitro/in vivo results	Ref.
Gold	N/A	N/A	20–1200	Intratumoral	Noticeable reduction in bladder tumor in mice.	[49]
Radioactive gold	N/A	N/A	N/A	Intratumoral	Noticeable reduction of tumor size achieved after 28 days with a single administration of the formulation and with minor radioactive leakage to other organs.	[50]
Gold	2	27	68	Intratumoral	High cytotoxicity in melanoma cell culture and in mice.	[51]
Gold	N/A	27	50	Oral	Nanoformulation stable in neutral pH with sustained release of 2 hours.; The in vitro and in vivo experiments revealed that the nanoformulation is highly effective in the cancer therapy.	[52]
Gold	N/A	N/A	65	N/A	Selective inhibition of smooth muscle cell migration.	[53]