Effects of Fungicides on Rat’s Neurosteroid Synthetic Enzymes

Figure 5

Docking analysis for the binding to rat’s AKR1C14 (1AFS). Panel (a): tebuconazole; blue structure, NADPH; red structure, testosterone; sky-blue structure, tebuconazole. Panel (b): triadimefon; blue structure, NADPH; green structure, dihydrotestosterone; sky-blue structure, triadimefon. Panel (c): vinclozolin; blue structure, NADPH; red structure, testosterone; sky-blue structure, vinclozolin.

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