Effects of Fungicides on Rat’s Neurosteroid Synthetic Enzymes

Table 1

The enzyme kinetic parameters and the half maximal inhibitory concentration (IC₅₀) of fungicides.

Parameters	5α-Red1	3α-HSD	RDH2
Apparent (µM)
Apparent (pmol/mg⋅min)
IC50 (µM)
Tebuconazole		~100	>100
Triadimefon			>100
Vinclozolin	NI	~100	NI

Mean ± SE, . NI: no inhibition at 100 µM.