Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability

<div>IR spectra of drug and physical mixture of drug and excipients. (a) IR spectrum of drug (Efavirenz). (b) IR spectrum of drug (efavirenz) + lipid (tripalmitin) + surfactant (poloxamer 188).</div>

BioMed Research International

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Figure 2: Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability 

Figure 2 | Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability 