Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability

<div>Contour plots, 3D surface plots, and overlay plot for process variables. (a) Contour plot for particle size. (b) 3D surface plot of particle size. (c) Contour plot for PDI. (d) 3D surface plot of PDI. (e) Overlay plot for optimization.</div>

BioMed Research International

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Figure 3: Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability 

Figure 3 | Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability 