Research Article

Systematic Approach for the Formulation and Optimization of Solid Lipid Nanoparticles of Efavirenz by High Pressure Homogenization Using Design of Experiments for Brain Targeting and Enhanced Bioavailability

Table 2

Major peaks observed in the IR spectrum of efavirenz recorded using FT-IR spectrophotometer (Bruker Alpha-One, Bruker Optik, Germany).

Observed (cm−1)Reported (cm−1)Inference

3319.643500–3100N-H stretching
2249.392250–2100C≡C (alkyne)
1750.061750–1730C=O of ester
1602.591680–1630C=O of amide
1498.331350–1000C-N
1036.161300–1000C-O