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BioMed Research International
Volume 2017, Article ID 6071031, 11 pages
https://doi.org/10.1155/2017/6071031
Research Article

Recovery following Thyroxine Treatment Withdrawal, but Not Propylthiouracil, Averts In Vivo and Ex Vivo Thyroxine-Provoked Cardiac Complications in Adult FVB/N Mice

1Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, OH, USA
2Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA
3Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Cairo, Egypt

Correspondence should be addressed to Paul M. L. Janssen; ude.uso@01.nessnaj and Mohammad T. Elnakish; ude.uso@1.hsikanle

Received 20 March 2017; Revised 5 June 2017; Accepted 8 June 2017; Published 16 July 2017

Academic Editor: Natale Daniele Brunetti

Copyright © 2017 Nancy S. Saad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Steven J. Repas, Nancy S. Saad, Paul M. L. Janssen, and Mohammad T. Elnakish, “Memantine, an NMDA Receptor Antagonist, Prevents Thyroxin-induced Hypertension, but Not Cardiac Remodeling,” Journal of Cardiovascular Pharmacology, vol. 70, no. 5, pp. 305–313, 2017. View at Publisher · View at Google Scholar
  • Qiming Feng, Liping Zhang, and Teng Wang, “Necrostatin-1 Protects Against Paraquat-Induced Cardiac Contractile Dysfunction via RIP1-RIP3-MLKL-Dependent Necroptosis Pathway,” Cardiovascular Toxicology, pp. 1–10, 2018. View at Publisher · View at Google Scholar
  • Paul M. L. Janssen, and Mohammad T. Elnakish, “Modeling heart failure in animal models for novel drug discovery and development,” Expert Opinion on Drug Discovery, pp. 1–9, 2019. View at Publisher · View at Google Scholar