Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

Figure 2

((a), (b), and (c)) Expression of LC3-II, Beclin-1, P62, and p-AMPK by Western blotting assays in both groups before and after surgery. Data expressed as mean ± SD. –64. versus statin (Pre-OP); versus statin (Post-OP). ((d) and (e)) Expression of Beclin-1 and P62 by immunohistochemistry in both groups before and after surgery. Magnification 200x. Data expressed as mean ± SD, –64. versus statin (Pre-OP); versus statin (Post-OP).

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