Review Article

Advancements in Developing Strategies for Sterilizing and Functional HIV Cures

Figure 1

Two major strategies for HIV cure by using genome editing. (a) Gene therapy strategies to eradicate HIV reservoirs. Using ZFN, TALENS, or CRISPR to eliminate the HIV provirus in latent cells. (b) Gene therapy strategies to prevent susceptible cells from HIV infection. Using gene editing to modify the receptor of susceptible cells and protect them from HIV infection.
(a)
(b)