The Interaction of Selectins and PSGL-1 as a Key Component in Thrombus Formation and Cancer Progression

Table 1

Characteristics of various selectins.

	Cellular expression	Protein ligands	Rolling velocity of leukocytes
P-selectin; (GMP-140, PADGEM, CD62P)	Activated endothelium and platelets	PSGL-1; CD24	Slow
E-Selectin; (ELAM-1, CD62E)	Activated endothelium	PSGL-1; ESL-1; L-Selectin; Podocalyxin	Slow
L-Selectin; (MEL-14, CD62L)	Constitutive expression on leukocytes	PSGL-1; GlyCAM-1; MAdCAM-1; CD-34; Podocalyxin	Fast