Review Article
The Interaction of Selectins and PSGL-1 as a Key Component in Thrombus Formation and Cancer Progression
Table 1
Characteristics of various selectins.
| ā | Cellular expression | Protein ligands | Rolling velocity of leukocytes |
| P-selectin (GMP-140, PADGEM, CD62P) | Activated endothelium and platelets | PSGL-1 CD24 | Slow |
| E-Selectin (ELAM-1, CD62E) | Activated endothelium | PSGL-1 ESL-1 L-Selectin Podocalyxin | Slow |
| L-Selectin (MEL-14, CD62L) | Constitutive expression on leukocytes | PSGL-1 GlyCAM-1 MAdCAM-1 CD-34 Podocalyxin | Fast |
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