Endovenous Laser Ablation of Varicose Veins Preserves Biological Properties of Vascular Endothelium and Modulates Proinflammatory Agent Profile More Favorably Than Classic Vein Stripping

Figure 4

Concentration of proinflammatory agents in conditioned medium generated by endothelial cells subjected to serum from patients with varicose veins treated with classic vein stripping (CVS) and endovenous laser ablation (EVLA). Endothelial cells were subjected to 20% serum collected 6 h after surgery for 72 h and then they were washed and exposed for the next 72 h to serum-free medium to generate conditioned medium in which proinflammatory agents were quantified. Results (expressed as means ± SEM) derive from experiments performed with the sera from 12 patients per group. Asterisks indicate significant differences as compared with CVS.

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