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| Chemical name | Chemical ID | CAS RN | Interaction count | Organism count | Interaction | PubMed ID | Authors | Title | Year | Citation | Organism |
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| Tetrachlorodibenzodioxin | D013749 | 1746-01-6 | 18 | 3 | Tetrachlorodibenzodioxin affects the expression of ID3 mRNA | 23238561 | Nault et al. | Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice. | 2013 | Toxicol Appl Pharmacol. 2013 Mar 1; 267(2): 184-91. | Rattus norvegicus |
| | | | | | Tetrachlorodibenzodioxin cotreated with TIPARP gene mutant form results in decreased expression of ID3 mRNA | 21496263 | Dere et al. | Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7, and rat H4IIE hepatoma cells. | 2011 | BMC Genomics. 2011; 12: 193. | Rattus norvegicus |
| | | | | | Tetrachlorodibenzodioxin results in increased expression of ID3 mRNA | 19684285 | Kim et al. | Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells. | 2009 | Toxicol Sci. 2009 Nov; 112(1): 229-44. | Homo sapiens |
| | | | | | | 17942748 | Boverhof et al. | Inhibition of estrogen-mediated uterine gene expression responses by dioxin. | 2008 | Mol Pharmacol. 2008 Jan; 73(1): 82-93. | Rattus norvegicus |
| | | | | | | 15591033 | Watanabe et al. | Comparative uterine gene expression analysis after dioxin and estradiol administration. | 2004 | J Mol Endocrinol. 2004 Dec; 33(3): 763-71. | Rattus norvegicus |
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| Bisphenol A | C006780 | 80-05-7 | 5 | 3 | Bisphenol A results in increased expression of ID3 mRNA | 26982218 | Porreca et al. | “Stockpile” of slight transcriptomic changes determines the indirect genotoxicity of low-dose BPA in thyroid cells. | 2016 | PLoS One. 2016; 11(3): e0151618. | Rattus norvegicus |
| | | | | | | 25181051 | Ali et al. | Exposure to low-dose bisphenol A impairs meiosis in the rat seminiferous tubule culture model: a physiotoxicogenomic approach. | 2014 | PLoS One. 2014; 9(9): e106245. | Rattus norvegicus |
| | | | | | | 25270620 | Schaap et al. | A novel toxicogenomics-based approach to categorize (non)genotoxic carcinogens. | 2014 | Arch Toxicol. 2014 Oct 2. | Mus musculus |
| | | | | | | 16474171 | Buterin et al. | Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells. | 2006 | Carcinogenesis. 2006 Aug; 27(8): 1567-78. | Homo sapiens |
| | | | | | | 25912373 | Fic et al. | Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S. | 2015 | Toxicol In Vitro. 2015 Aug; 29(5): 1060-9. | Homo sapiens |
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| Ethinylestradiol | D004997 | 57-63-6 | 5 | 2 | Ethinylestradiol inhibits the reaction [IL1B protein results in increased expression of ID3 mRNA] | 12072388 | Evans et al. | Estrogen receptor alpha inhibits IL-1beta induction of gene expression in the mouse liver. | 2002 | Endocrinology. 2002 Jul; 143(7): 2559-70. | Mus musculus |
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| Benzo(a)pyrene | D001564 | 50-32-8 | 4 | 2 | Benzo(a)pyrene results in increased expression of ID3 mRNA | 22228805 | Kerley-Hamilton et al. | Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. | 2012 | Toxicol Sci. 2012 Apr; 126(2): 391-404. | Mus musculus |
| | | | | | | 20064835 | Sparfel et al. | Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene. | 2010 | Toxicol Sci. 2010 Apr; 114(2): 247-59. | Homo sapiens |
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| Coumestrol | D003375 | 479-13-0 | 3 | 1 | Coumestrol cotreated with 2,3-bis(3′-hydroxybenzyl)butyrolactone results in decreased expression of ID3 mRNA | | | | | | |
| | | | | | Coumestrol cotreated with resveratrol results in decreased expression of ID3 mRNA | 19167446 | Dip et al. | Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens. | 2009 | Food Chem Toxicol. 2009 Apr; 47(4): 787-95. | Homo sapiens |
| | | | | | Coumestrol results in decreased expression of ID3 mRNA | | | | | | |
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| Genistein | D019833 | 446-72-0 | 3 | 1 | | | | | | | |
| | | | | | Genistein results in increased expression of ID3 mRNA | 22228119 | Di et al. | A high concentration of genistein downregulates activin A, Smad3, and other TGF-Î2 pathway genes in human uterine leiomyoma cells. | 2012 | Exp Mol Med. 2012 Apr 30; 44(4): 281-92. | Homo sapiens |
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| Titanium dioxide | C009495 | 13463-67-7 | 3 | 2 | Titanium dioxide results in increased expression of ID3 mRNA | 23131501 | Gao et al. | Ovarian dysfunction and gene-expressed characteristics of female mice caused by long-term exposure to titanium dioxide nanoparticles. | 2012 | J Hazard Mater. 2012 Dec; 243: 19-27. | Mus musculus |
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| 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | C049584 | 105650-23-5 | 2 | 1 | 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ID3 mRNA | 15059925 | Fujiwara et al. | Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2004 | Carcinogenesis. 2004 Aug; 25(8): 1495-505. | Rattus norvegicus |
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| Carbon tetrachloride | D002251 | 56-23-5 | 2 | 2 | Carbon tetrachloride affects the expression of ID3 mRNA | 12734012 | Kriete et al. | Combined histomorphometric and gene expression profiling applied to toxicology. | 2003 | Genome Biol. 2003; 4(5): R32. | Rattus norvegicus |
| | | | | | Carbon tetrachloride results in increased expression of ID3 mRNA | 27339419 | Godoy et al. | Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. | 2016 | Arch Toxicol. 2016 Jun 23. | Mus musculus |
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| Vehicle emissions | D001335 | | 2 | 2 | Vehicle emissions result in increased methylation of ID3 gene | 25560391 | Tachibana et al. | Prenatal diesel exhaust exposure disrupts the DNA methylation profile in the brain of mouse offspring. | 2015 | J Toxicol Sci. 2015 Feb; 40(1): 1-11. | Mus musculus |
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| 1,1-Dimethylbutyl-1-deoxy-delta(9)-THC | C432747 | | 1 | 1 | 1,1-Dimethylbutyl-1-deoxy-delta(9)-THC results in decreased expression of ID3 mRNA | 15313899 | Blázquez et al. | Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. | 2004 | Cancer Res. 2004 Aug 15; 64(16): 5617-23. | Mus musculus |
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| 1,2-Dithiol-3-thione | C049325 | 534-25-8 | 1 | 1 | 1,2-Dithiol-3-thione results in decreased expression of ID3 mRNA | 19162173 | Ren et al. | Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species. | 2009 | Reprod Toxicol. 2009 Jun; 27(3-4): 266-77. | Rattus norvegicus |
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| 2-(1′H-Indolo-3′-carbonyl)thiazole-4-carboxylic acid methyl ester | C548651 | | 1 | 1 | 2-(1′H-Indolo-3′-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of ID3 mRNA | 19162173 | Ren et al. | Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species. | 2009 | Reprod Toxicol. 2009 Jun; 27(3-4): 266-77. | Rattus norvegicus |
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| 2,3-Bis(3′-hydroxybenzyl)butyrolactone | C029497 | 76543-15-2 | 1 | 1 | Coumestrol cotreated with 2,3-bis(3′-hydroxybenzyl)butyrolactone results in decreased expression of ID3 mRNA | 19167446 | Dip et al. | Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens. | 2009 | Food Chem Toxicol. 2009 Apr; 47(4): 787-95. | Homo sapiens |
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| Diethylstilbestrol | D004054 | 56-53-1 | 1 | 1 | Diethylstilbestrol results in decreased expression of ID3 mRNA | 26865669 | Ryan et al. | Moving toward integrating gene expression profiling into high-throughput testing: a gene expression biomarker accurately predicts estrogen receptor α modulation in a microarray compendium. | 2016 | Toxicol Sci. 2016 May; 151(1): 88-103. | Homo sapiens |
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| Ethyl methanesulfonate | D005020 | 62-50-0 | 1 | 1 | Ethyl methanesulfonate results in decreased expression of ID3 mRNA | 24211769 | Sakai et al. | Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity. | 2014 | Toxicology. 2014 Jan 6; 315: 8-16. | Homo sapiens |
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| Hexestrol | D006589 | 5635-50-7 | 1 | 1 | Hexestrol results in decreased expression of ID3 mRNA | 26865669 | Ryan et al. | Moving toward integrating gene expression profiling into high-throughput testing: a gene expression biomarker accurately predicts estrogen receptor α modulation in a microarray compendium. | 2016 | Toxicol Sci. 2016 May; 151(1): 88-103. | Homo sapiens |
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| Hydrogen peroxide | D006861 | 7722-84-1 | 1 | 1 | Hydrogen peroxide affects the expression of ID3 mRNA | 20044591 | Briedé et al. | Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. | 2010 | Toxicol Sci. 2010 Apr; 114(2): 193-203. | Homo sapiens |
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| Iodoacetic acid | D019807 | 64-69-7 | 1 | 1 | Iodoacetic acid results in decreased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Iopanoic acid | D007480 | 96-83-3 | 1 | 1 | Iopanoic acid results in decreased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Lead acetate | C008261 | 301-04-2 | 1 | 1 | Lead acetate results in decreased expression of ID3 mRNA | 25270620 | Schaap et al. | A novel toxicogenomics-based approach to categorize (non)genotoxic carcinogens. | 2014 | Arch Toxicol. 2014 Oct 2. | Mus musculus |
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| Lithium chloride | D018021 | 7447-41-8 | 1 | 1 | Lithium chloride results in decreased expression of ID3 mRNA | 15711924 | Zhang et al. | Early gene response in lithium chloride induced apoptosis. | 2005 | Apoptosis. 2005 Jan; 10(1): 75-90. | Homo sapiens |
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| Methoxyacetic acid | C013598 | 625-45-6 | 1 | 1 | Methoxyacetic acid results in increased expression of ID3 mRNA | 20864626 | Robinson et al. | Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture. | 2010 | Toxicol Sci. 2010 Dec; 118(2): 675-85. | Rattus norvegicus |
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| Methoxychlor | D008731 | 72-43-5 | 1 | 1 | Methoxychlor results in decreased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Methylcholanthrene | D008748 | 56-49-5 | 1 | 1 | Methylcholanthrene results in increased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Methylmercuric chloride | C004925 | 115-09-3 | 1 | 1 | Methylmercuric chloride results in increased expression of ID3 mRNA | 20864626 | Robinson et al. | Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture. | 2010 | Toxicol Sci. 2010 Dec; 118(2): 675-85. | Rattus norvegicus |
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| Methylmercury compounds | D008767 | | 1 | 1 | Methylmercury compounds result in increased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Methyl methanesulfonate | D008741 | 66-27-3 | 1 | 1 | Methyl methanesulfonate results in decreased expression of ID3 mRNA | 24211769 | Sakai et al. | Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity. | 2014 | Toxicology. 2014 Jan 6; 315: 8-16. | Homo sapiens |
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| Methylnitrosourea | D008770 | 684-93-5 | 1 | 1 | Methylnitrosourea results in decreased expression of ID3 mRNA | 25270620 | Schaap et al. | A novel toxicogenomics-based approach to categorize (non)genotoxic carcinogens. | 2014 | Arch Toxicol. 2014 Oct 2. | Mus musculus |
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| Monobutyl phthalate | C028577 | 131-70-4 | 1 | 1 | Monobutyl phthalate results in increased expression of ID3 mRNA | 20864626 | Robinson et al. | Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture. | 2010 | Toxicol Sci. 2010 Dec; 118(2): 675-85. | Rattus norvegicus |
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| Mustard gas | D009151 | 505-60-2 | 1 | 1 | Mustard gas results in increased expression of ID3 mRNA | 15674844 | Sabourin et al. | Time- and dose-dependent analysis of gene expression using microarrays in sulfur mustard-exposed mice. | 2004 | J Biochem Mol Toxicol. 2004; 18(6): 300-12. | Mus musculus |
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| n-Butoxyethanol | C017096 | 111-76-2 | 1 | 1 | n-Butoxyethanol results in decreased expression of ID3 mRNA | 19812364 | Laifenfeld et al. | The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma. | 2010 | Toxicol Sci. 2010 Jan; 113(1): 254-66. | Mus musculus |
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| Nickel sulfate | C029938 | 7786-81-4 | 1 | 1 | Nickel sulfate results in increased expression of ID3 mRNA | 22714537 | Clancy et al. | Gene expression changes in human lung cells exposed to arsenic, chromium, nickel, or vanadium indicate the first steps in cancer. | 2012 | Metallomics. 2012 Aug; 4(8): 784-93. | Homo sapiens |
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| Nitrosobenzylmethylamine | C014707 | 937-40-6 | 1 | 1 | Nitrosobenzylmethylamine results in increased expression of ID3 mRNA | 17616710 | Reen et al. | Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus. | 2007 | Cancer Res. 2007 Jul 1; 67(13): 6484-92. | Rattus norvegicus |
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| N-Nitrosomorpholine | C002741 | 59-89-2 | 1 | 1 | N-Nitrosomorpholine results in increased expression of ID3 mRNA | 19716841 | Oberemm et al. | Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters. | 2009 | Toxicol Appl Pharmacol. 2009 Dec 1; 241(2): 230-45. | Rattus norvegicus |
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| Octylmethoxycinnamate | C118580 | | 1 | 1 | Octylmethoxycinnamate results in decreased expression of ID3 mRNA | 23397585 | Song et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch Toxicol. 2013 Jun; 87(6): 1103-13. | Homo sapiens |
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| Oxophenylarsine | C029341 | 637-03-6 | 1 | 1 | Oxophenylarsine binds to ID3 protein | 23523789 | Kurooka et al. | The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues. | 2013 | Biochem Biophys Res Commun. 2013 Apr 19; 433(4): 579-85. | Mus musculus |
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| Perfluorooctanoic acid | C023036 | 335-67-1 | 1 | 1 | Perfluorooctanoic acid results in decreased expression of ID3 mRNA | 19162173 | Ren et al. | Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species. | 2009 | Reprod Toxicol. 2009 Jun; 27(3-4): 266-77. | Rattus norvegicus |
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| Phenol | D019800 | 108-95-2 | 1 | 1 | Phenol results in increased expression of ID3 mRNA | 17547211 | Kawata et al. | Classification of heavy-metal toxicity by human DNA microarray analysis. | 2007 | Environ Sci Technol. 2007 May 15; 41(10): 3769-74. | Homo sapiens |
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| Polychlorinated biphenyls | D011078 | | 1 | 1 | Polychlorinated biphenyls analog results in decreased expression of ID3 mRNA | 16474171 | Buterin et al. | Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells. | 2006 | Carcinogenesis. 2006 Aug; 27(8): 1567-78. | Homo sapiens |
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| Propiconazole | C045950 | 60207-90-1 | 1 | 1 | Propiconazole results in decreased expression of ID3 mRNA | 21278054 | Nesnow et al. | Propiconazole induces alterations in the hepatic metabolome of mice: relevance to propiconazole-induced hepatocarcinogenesis. | 2011 | Toxicol Sci. 2011 Apr; 120(2): 297-309. | Mus musculus |
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| Vanadyl sulfate | C034028 | 27774-13-6 | 1 | 1 | Vanadyl sulfate results in decreased expression of ID3 mRNA | 16330358 | Li et al. | Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells. | 2005 | Environ Health Perspect. 2005 Dec; 113(12): 1747-54. | Homo sapiens |
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| Vinclozolin | C025643 | 50471-44-8 | 1 | 1 | Vinclozolin results in increased expression of ID3 mRNA | 23034163 | Skinner et al. | Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions. | 2012 | Genome Biol. 2012; 13(10): R91. | Rattus norvegicus |
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| Ethylnitrosourea | D005038 | 759-73-9 | 1 | 1 | Ethylnitrosourea results in increased expression of ID3 mRNA | 15954086 | Katayama et al. | Microarray analysis of genes in fetal central nervous system after ethylnitrosourea administration. | 2005 | Birth Defects Res B Dev Reprod Toxicol. 2005 Jun; 74(3): 255-60. | Rattus norvegicus |
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| 2,6-Dinitrotoluene | C023514 | 606-20-2 | 1 | 1 | 2,6-Dinitrotoluene affects the expression of ID3 mRNA | 21346803 | Deng et al. | Analysis of common and specific mechanisms of liver function affected by nitrotoluene compounds. | 2011 | PLoS One. 2011; 6(2): e14662. | Rattus norvegicus |
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| 3,4-Dichloroaniline | C014464 | 95-76-1 | 1 | 1 | 3,4-Dichloroaniline results in decreased expression of ID3 mRNA | 24172598 | Da Rocha et al. | Diuron metabolites and urothelial cytotoxicity: in vivo, in vitro, and molecular approaches. | 2013 | Toxicology. 2013 Dec 15; 314(2-3): 238-46. | Homo sapiens |
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| 4,4′-Hexafluoroisopropylidene diphenol | C583074 | | 1 | 1 | 4,4′-Hexafluoroisopropylidene diphenol results in increased expression of ID3 mRNA | 25912373 | Fic et al. | Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S. | 2015 | Toxicol In Vitro. 2015 Aug; 29(5): 1060-9. | Homo sapiens |
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| 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | D015123 | 55097-80-8 | 1 | 1 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ID3 mRNA | 19150397 | Lu et al. | Early whole-genome transcriptional response induced by benzo[a]pyrene diol epoxide in a normal human cell line. | 2009 | Genomics. 2009 Apr; 93(4): 332-42. | Homo sapiens |
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| Bis(4-hydroxyphenyl)sulfone | C543008 | 80-09-1 | 1 | 1 | Bis(4-hydroxyphenyl)sulfone results in increased expression of ID3 mRNA | 25912373 | Fic et al. | Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S. | 2015 | Toxicol In Vitro. 2015 Aug; 29(5): 1060-9. | Homo sapiens |
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| Bismuth tripotassium dicitrate | C002791 | 57644-54-9 | 1 | 1 | Bismuth tripotassium dicitrate results in increased expression of ID3 mRNA | 15912405 | Magnusson et al. | Gene expression changes induced by bismuth in a macrophage cell line. | 2005 | Cell Tissue Res. 2005 Aug; 321(2): 195-210. | Rattus norvegicus |
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| tert-Butylhydroperoxide | D020122 | 75-91-2 | 1 | 1 | tert-Butylhydroperoxide results in increased expression of ID3 mRNA | 15003993 | Ma et al. | The effect of stress withdrawal on gene expression and certain biochemical and cell biological properties of peroxide-conditioned cell lines. | 2004 | FASEB J. 2004 Mar; 18(3): 480-8. | Mus musculus |
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| C646 compound | C584509 | | 1 | 1 | C646 compound results in decreased expression of ID3 mRNA | 26191083 | Gaddis et al. | Altering cancer transcriptomes using epigenomic inhibitors. | 2015 | Epigenetics Chromatin. 2015; 8: 9. | Homo sapiens |
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| Cadmium sulfate | C037123 | 10124-36-4 | 1 | 1 | Cadmium sulfate affects the reaction [MTF1 affects the expression of ID3 mRNA] | 16221973 | Wimmer et al. | Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. | 2005 | Nucleic Acids Res. 2005; 33(18): 5715-27. | Mus musculus |
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| Cobaltous chloride | C018021 | 7646-79-9 | 1 | 1 | Cobaltous chloride results in decreased expression of ID3 mRNA | 19320972 | Hang et al. | Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array. | 2009 | BMC Genomics. 2009; 10: 126. | Homo sapiens |
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| Copper sulfate | D019327 | 7758-98-7 | 1 | 1 | Copper sulfate results in increased expression of ID3 mRNA | 19549813 | Song et al. | Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper. | 2009 | Physiol Genomics. 2009 Aug 7; 38(3): 386-401. | Homo sapiens |
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| Cuprizone | D003471 | 370-81-0 | 1 | 1 | Cuprizone affects the expression of ID3 mRNA | 26577399 | Abe et al. | Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats. | 2016 | Toxicol Appl Pharmacol. 2016 Jan 1; 290: 10-20. | Rattus norvegicus |
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| Sodium arsenite | C017947 | 13768-07-5 | 9 | 2 | ID3 protein inhibits the reaction [sodium arsenite results in increased expression of EGR1 mRNA] | 23523789 | Kurooka et al. | The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues. | 2013 | Biochem Biophys Res Commun. 2013 Apr 19; 433(4): 579-85. | Mus musculus |
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| Sodium arsenite | | | | | Leptomycin B inhibits the reaction [sodium arsenite affects the localization of ID3 protein] | 23523789 | Kurooka et al. | The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues. | 2013 | Biochem Biophys Res Commun. 2013 Apr 19; 433(4): 579-85. | Mus musculus |
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| Sodium arsenite | | | | | Sodium arsenite affects the localization of ID3 protein | 16966095 | McNeely et al. | Exit from arsenite-induced mitotic arrest is p53 dependent. | 2006 | Environ Health Perspect. 2006 Sep; 114(9): 1401-6. | Homo sapiens |
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| Sodium arsenite | | | | | Sodium arsenite binds to ID3 protein | 12760830 | Andrew et al. | Genomic and proteomic profiling of responses to toxic metals in human lung cells. | 2003 | Environ Health Perspect. 2003 May; 111(6): 825-35. | Homo sapiens |
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| Sodium arsenite | | | | | Sodium arsenite which binds to ID3 protein promotes the reaction [XPO1 protein affects the localization of ID3 protein] | 23523789 | Kurooka et al. | The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues. | 2013 | Biochem Biophys Res Commun. 2013 Apr 19; 433(4): 579-85. | Mus musculus |
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| Sodium arsenite | | | | | Sodium arsenite results in increased expression of ID3 mRNA | 16966095 | McNeely et al. | Exit from arsenite-induced mitotic arrest is p53 dependent. | 2006 | Environ Health Perspect. 2006 Sep; 114(9): 1401-6. | Homo sapiens |
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| Cadmium chloride | D019256 | 10108-64-2 | 2 | 2 | Cadmium chloride results in increased expression of ID3 mRNA | 16221973 | Wimmer et al. | Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. | 2005 | Nucleic Acids Res. 2005; 33(18): 5715-27. | Mus musculus |
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| Diethylhexyl phthalate | D004051 | 117-81-7 | 2 | 1 | Diethylhexyl phthalate results in decreased expression of ID3 mRNA | 19850644 | Ren et al. | Characterization of peroxisome proliferator-activated receptor alpha-independent effects of PPAR-alpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor. | 2010 | Toxicol Sci. 2010 Jan; 113(1): 45-59. | Mus musculus |
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