HPV Status and Its Correlation with BCL2, p21, p53, Rb, and Survivin Expression in Breast Cancer in a Chinese Population

Figure 1

Detection of HR-HPV in 81 fresh breast cancer samples using HC2 assay. HPV signals were measured as relative light units (RLUs) with light intensity indicating the presence or absence of target DNA in the tested specimen. RLU measurements equal to or higher than the cutoff (CO) value (RLU/CO ≥ 1) indicated the presence of HPV DNA in the sample. RLU = CO indicates approximately 5,000 virus copies in the specimen. The prevalence of high-risk HPVs detected by HC2 was 17.3% (14/81) in breast cancer samples.