HPV Status and Its Correlation with BCL2, p21, p53, Rb, and Survivin Expression in Breast Cancer in a Chinese Population

Figure 2

Representative images of IHC assays analyzing the expression of BCL2, p21, p53, Rb, and survivin in breast cancer tissues. BCL2 mainly showed cytoplasmic staining (a-b). Positive staining of P21 (c-d), p53 (e-f), and Rb (g-h) was observed in cell nuclei. Survivin staining (i-j) was seen in the cytoplasm and/or nucleus. High expression of BCL2 and survivin was seen in 26.0% and 23.5% of the cases, respectively. P21 positive expression was observed in 18.5% of the cases, p53 in 79.0% of the cases, and Rb in 64.5% of the cases.