HPV Status and Its Correlation with BCL2, p21, p53, Rb, and Survivin Expression in Breast Cancer in a Chinese Population

Table 1

Relationship between HPV and clinicopathological parameters in breast cancers.

Features		HPV
		Negative	Positive
Age (y)
≤50	45	40	5
>50	36	27	9	0.140
Histological type
DCIS	11	9	2
IDC	64	52	12
Others	6	6	0	0.508
Grade
II	47	37	10
III	17	15	2	0.490
Unknown	17
Tumor size (cm)
≤2	43	36	7
>2	35	28	7	0.770
Unknown	3
Lymph node metastasis
Negative	53	43	10
Positive	28	24	4	0.761
ER
Negative	18	16	2
Positive	63	51	12	0.724
PR
Negative	24	20	4
Positive	57	47	10	0.793
HER2
Negative	52	44	8
Positive	15	13	2	1.000
Unknown	14
Ki-67
Negative	29	23	6
Positive	52	44	8	0.554

DCIS: ductal carcinomas in situ; IDC: invasive ductal carcinoma; Others: invasive lobular carcinomas, mucinous adenocarcinomas, and papillary carcinoma.