Research Article

miR-31 Functions as an Oncomir Which Promotes Epithelial-Mesenchymal Transition via Regulating BAP1 in Cervical Cancer

Figure 4

The effect of miR-31 and BAP1 on the tumorigenicity in nude mice xenograft. (a) HeLa cells were transfected with BAP1 plasmid or control plasmid. The tumors were collected on day 35 after implantation (left); tumor volume was measured at the end of the experiment (right). (b) Statistical analysis of the tumor weight. (c) Quantitative RT-PCR analysis of miR-31 and BAP1 in the tumors from different implanted mice. (d) BAP1 expression was measured by IHC in different xenograft tissues. The scale bar represents 50 μm. ,.
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