Research Article

Asymmetric Dimethylarginine Induced Apoptosis and Dysfunction of Endothelial Progenitor Cells: Role of Endoplasmic Reticulum Stress Pathway

Figure 5

Role of the ER stress pathway in ADMA-induced apoptosis and dysfunction of EPCs. (a and b) Representative western blots and quantification of Phospho-PERK, GRP78, and CHOP. The levels of Phospho-PERK, GRP78, and CHOP were all upregulated after incubation with ADMA (5~50 μmol/L) for 24 h. Mean ± SEM. versus control.