| | Time point | Top 10 DEGs between sham-injury and injury in lesion centre | Top 10 pathways between sham-injury and injury in lesion centre |
| | 0.5 h | Npas4, Gm2083, Socs3, Socs3, Fosb, Ccl3, II6, Cyr61, Ptgs2, Myh1 | Pathways in cancer, MAPK signaling pathway, Transcriptional misregulation in cancer, focal adhesion, proteoglycans in cancer, PI3K-Akt signaling pathway, hippo signaling pathway, HTLV-I infection, regulation of actin cytoskeleton, metabolic pathways |
| | 4 h | Ucn2, Gm2083, Atf3, Hspa1b, Hspa1b, Ccl3, C330006P03Rik, Hspa1a, Hspa1b, Egr3 | Metabolic pathways, MAPK signaling pathway, pathways in cancer, PI3K-Akt signaling pathway, HTLV-I infection, focal adhesion, proteoglycans in cancer, osteoclast differentiation, transcriptional misregulation in cancer, olfactory transduction |
| | 24 h | Gm2083, Socs3, Chi3l3, Adam8, Gp49a, Hmox1, Serpine1, Tgm1, A130040M12Rik, Tnc | Metabolic pathways, MAPK signaling pathway, pathways in cancer, HTLV-I infection, PI3K-Akt signaling pathway, focal adhesion, protein processing in endoplasmic reticulum, regulation of actin cytoskeleton, Epstein-Barr virus infection, proteoglycans in cancer |
| | 3 d | Gpnmb, Cd36, Abca1, Cd5l, Cd36, Ccnb1, Thbs1, Rrm2, Rrm2, Sprr1a | Metabolic pathways, HTLV-I infection, pathways in cancer, focal adhesion, regulation of actin cytoskeleton, PI3K-Akt signaling pathway, proteoglycans in cancer, MAPK signaling pathway, lysosome, osteoclast differentiation |
| | 7 d | Gpnmb, Gp49a, Cd36, Cd36, Ms4a7, Cd5l, C3ar1, Clec7a, Cd68, Atp6v0d2 | Focal adhesion, PI3K-Akt signaling pathway, metabolic pathways, pathways in cancer, proteoglycans in cancer, MAPK signaling pathway, regulation of actin cytoskeleton, osteoclast differentiation, HTLV-I infection, tuberculosis |
| | 28 d | Gpnmb, Clec7a, Cst7, Gp49a, Lgals3, Cd68, C3ar1, Ms4a7, Sprr1a, Cd48 | Metabolic pathways, MAPK signaling pathway, pathways in cancer, HTLV-I infection, focal adhesion, proteoglycans in cancer, PI3K-Akt signaling pathway, regulation of actin cytoskeleton, chemokine signaling pathway, phagosome |
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