Research Article

In Vitro and In Vivo Evaluation of Commercially Available Fibrin Gel as a Carrier of Alendronate for Bone Tissue Engineering

Figure 2

(a) Gross view of fibrin gels containing various ALN concentrations (10−4 M~10−7 M). (b) Effects of ALN concentration on the stiffness of fibrin/ALN gel. The stiffness of the fibrin/ALN gel was not significantly affected by ALN concentration. (c) In vitro cumulative release of ALN from fibrin gel. A slow sustained release was observed. The data shown are the mean ± standard deviation (SD) of three independent experiments.
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