Research Article
In Vitro and In Vivo Evaluation of Commercially Available Fibrin Gel as a Carrier of Alendronate for Bone Tissue Engineering
Figure 6
Effect of fibrin/ALN gel on new bone formation in a rabbit calvarial defect. Representative three-dimensional microcomputer tomography images (a) and quantification graph (b) of calvarial bone defect regeneration at 2, 4, and 8 weeks after implantation with fibrin gel or fibrin/ALN gel. The new bone formation increased in the fibrin/ALN gel (10−6 M ALN) group compared to that in the fibrin gel-implanted group. Scale bar = 3 mm. The data shown are the mean ± standard deviation (SD). compared with the fibrin gel-implanted group.
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