BioMed Research International / 2017 / Article / Tab 2

Research Article

Comparison of Host Gene Expression Profiles in Spleen Tissues of Genetically Susceptible and Resistant Mice during ECTV Infection

Table 2

List of 10 DEGs that were most up- or downregulated in BALB/c and C57BL/6 during ECTV infection.

Mouse strainBALB/cC57BL/6
After infection3 dpi versus uninfected10 dpi versus uninfected3 dpi versus uninfected10 dpi versus uninfected
Gene categoryGeneFold changeGeneFold changeGeneFold changeGeneFold change

UpregulatedKap5.65Spp146.2Xist27.28Xist50.37
Hspa1b4.39Gzmb39.4Ttr4.49Hspa1b26.23
Gbp14.32Ifng24.2Tsks3.13Gzmb22.26
Gdi23.99Vcan20.7Mettl11a2.93Gbp117.84
Apol7c3.95Mmp317.9Hspa1b2.81Hspa1a15.25
Slfn43.60Nts16.5Ptger12.68Ctsg14.02
Gbp23.57Timp114.0Alb2.59Mcpt810.06
Ddx63.47Gzmd13.6Ifnz2.34Rgs18.74
Iigp13.42Saa313.6Dppa5a2.32Gzmk7.71
Acaa23.41Cxcl512.6Cml32.29Prtn37.03

DownregulatedVmn1r1480.33Ctrb10.08Psap0.29Bpgm0.17
Phxr50.33Try40.02Cyp4f160.28Dbp0.17
Reg20.32Cpb10.03Foxp10.28Igfbp50.17
Psg280.29Cela3b0.03Epsti10.28Ccr90.16
Mup100.28Marco0.03Abhd120.27Apol7c0.16
Astx0.25Clps0.04Kap0.27Kdm5d0.16
Adipoq0.25Zg160.05Tpm30.26Cyr610.15
Cfd0.16Emr40.06Ddx3y0.25Ddx3y0.14
Car30.08Pnlip0.02Sh3bgrl0.25Eif2s3y0.13
Mettl11a0.06Amy2a10.006Hmgcs10.22Igfbp30.12

The DEGs were ranked by fold change and those were the most (fold change) up- or downregulated in expression at 3 and 10 dpi in BALB/c and C57BL/6 mice.

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