Comparison of Host Gene Expression Profiles in Spleen Tissues of Genetically Susceptible and Resistant Mice during ECTV Infection

Table 3

The interferon-stimulated genes (ISGs) that were upregulated in BALB/c and C57BL/6 during ECTV infection.

Genes			3 dpi		10 dpi
Gene symbol	RefSeq	Gene name
OASL1	AB067533	2′-5′-Oligoadenylate synthetase-like 1	1.91	0.82	3.34	1.21
OAS2	AB067535	2′-5′-Oligoadenylate synthetase 2	1.90	1.13	4.15	1.23
IGTP	NM_018738	Interferon gamma induced GTPase	2.03	0.88	2.48	2.39
IFI47	NM_008330	Interferon gamma inducible protein 47	2.07	0.81	2.60	1.66
IFIT2	NM_008332	Interferon-induced protein with tetratricopeptide repeats 2	1.54	0.80	3.69	1.29
IIGP1	BM239828	Interferon inducible GTPase 1	3.42	0.96	5.32	3.64
IFI204	NM_008329	Interferon activated gene 204	1.52	0.85	6.10	2.16
IFI202B	NM_011940	Interferon activated gene 202B	1.49	0.90	4.00	1.15
IFI44	BB329808	Interferon-induced protein 44	2.49	0.89	4.93	2.42
IFITM1	BC027285	Interferon induced transmembrane protein 1	1.03	0.95	2.10	1.36
IFITM3	BC010291	Interferon induced transmembrane protein 3	1.09	1.13	1.73	1.49
IFITM6	BB193024	Interferon induced transmembrane protein 6	1.18	1.15	1.92	1.86
IFIH1	AY075132	Interferon induced with helicase C domain 1	1.57	1.17	1.82	1.42
ISG15	AK019325	Interferon-stimulated protein (15 kda)	1.73	1.22	1.93	0.92
GBP1	NM_010259	Guanylate binding protein 1	4.32	0.86	6.60	17.84
GBP2	NM_010260	Guanylate binding protein 2	3.60	0.82	7.15	3.28
GBP3	NM_018734	Guanylate binding protein 3	1.82	0.98	3.27	2.l0
GBP7	BC010229	Guanylate binding protein 7	2.39	1.04	3.61	2.44
GBP8	NM_029509	Guanylate binding protein 8	1.69	1.21	2.24	3.20
MX1	M21039	Myxovirus resistance 1	1.29	1.16	3.30	1.05
EIF2αK2	AV328340	Eukaryotic translation initiation factor 2-α kinase 2	2.17	0.97	2.49	0.91
CH25H	NM_009890	Cholesterol 25-hydroxylase	0.97	0.84	2.68	0.84

The interferon-stimulated genes (ISGs) differentially expressed in BALB/c and/or C57BL/6 were selected for analysis at 3 and 10 dpi. The capital “B” and “C” represent BALB/c and C57BL/6 mice, respectively. Superscripts “i” and “u” represent infected and uninfected mice, respectively.