Comparison of Host Gene Expression Profiles in Spleen Tissues of Genetically Susceptible and Resistant Mice during ECTV Infection
Table 4
The cytokines that were upregulated in BALB/c and C57BL/6 during ECTV infectio.
Genes
3 dpi
10 dpi
Gene symbol
RefSeq
Gene name
IFN-γ
K00083
Interferon gamma
0.95
0.89
24.17
5.21
IFN-ζ
BF022827
Interferon zeta
0.44
2.34
0.89
1.00
IFN-α2
NM_010503
Interferon alpha 2
0.79
1.76
0.82
1.54
GzmA
NM_010370
Granzyme A
0.68
1.83
1.13
5.51
GzmB
NM_013542
Granzyme B
1.12
0.87
39.39
22.26
GzmC
NM_010371
Granzyme C
0.92
0.89
5.96
0.96
GzmD
NM_010372
Granzyme D
1.07
0.95
13.63
1.02
GzmE
NM_010373
Granzyme E
1.33
0.98
10.21
1.07
GzmF
NM_010374
Granzyme F
0.88
0.99
2.68
1.22
GzmK
AB032200
Granzyme K
0.61
0.93
7.52
7.71
KLRG1
NM_016970
Killer cell lectin-like receptor subfamily G, member 1
0.67
1.17
1.06
3.56
KLRC1
AF106008
Killer cell lectin-like receptor subfamily C, member 1
1.19
0.67
5.57
1.89
KLRK1
AF039026
Killer cell lectin-like receptor subfamily K, member 1
1.13
1.13
2.72
2.15
CXCL1
NM_008176
Chemokine (C-X-C motif) ligand 1
2.43
1.16
7.16
1.99
CXCL5
NM_009141
Chemokine (C-X-C motif) ligand 5
2.83
0.90
12.61
1.86
CXCL9
NM_008599
Chemokine (C-X-C motif) ligand 9
1.45
1.07
3.99
2.86
CXCL10
NM_021274
Chemokine (C-X-C motif) ligand 10
2.41
0.93
5.46
2.21
CXCL11
NM_019494
Chemokine (C-X-C motif) ligand 11
1.47
1.11
5.19
1.07
CCL2
AF065933
Chemokine (C-C motif) ligand 2
1.14
1.11
5.86
1.15
CCL3
NM_011337
Chemokine (C-C motif) ligand 3
1.73
0.97
12.46
4.52
CCL4
AF128218
Chemokine (C-C motif) ligand 4
0.85
1.23
4.65
2.72
CCL6
AV084904
Chemokine (C-C motif) ligand 6
1.68
0.73
3.04
0.90
CCL7
AF128193
Chemokine (C-C motif) ligand 7
0.98
0.95
3.34
1.79
CCL8
NM_021443
Chemokine (C-C motif) ligand 8
0.85
1.26
4.16
4.29
CCL12
U50712
Chemokine (C-C motif) ligand 12
1.08
1.35
4.81
1.41
IL1-α
BC003727
Interleukin 1 alpha
1.06
1.08
1.33
1.74
IL1R2
NM_010555
Interleukin 1 receptor, type II
1.45
0.89
8.99
1.99
IL1F9
AY071843
Interleukin 1 family, member 9
1.23
1.90
0.77
1.71
IL1RAP
NM_134103
Interleukin 1 receptor accessory protein
1.30
1.17
1.95
1.65
IL1RN
M57525
Interleukin 1 receptor antagonist
1.17
0.75
2.73
1.06
IL2R-β
M28052
Interleukin 2 receptor, β chain
1.11
0.56
2.64
0.95
IL2R-α
AF054581
Interleukin 2 receptor, α chain
1.03
0.70
5.48
0.54
IL12R-β1
NM_008353
Interleukin 12 receptor, β1
1.15
0.97
2.65
1.59
IL33
NM_133775
Interleukin 33
1.05
0.84
3.83
0.81
STAT1
BB229853
Signal transducer and activator of transcription 1
2.97
0.80
6.34
1.11
STAT2
AF088862
Signal transducer and activator of transcription 2
1.77
1.01
2.04
1.60
STAT3
BG069527
Signal transducer and activator of transcription 3
1.50
1.38
2.73
0.93
TNFRSF9
BC028507
Tumor necrosis factor receptor superfamily, member 9
1.03
0.97
6.23
1.06
The cytokines differentially expressed in BALB/c and/or C57BL/6 were selected for analysis at 3 and 10 dpi. The capital “B” and “C” represent BALB/c and C57BL/6 mice, respectively. Superscripts “i” and “u” represent infected and uninfected mice, respectively.
