Effects of Pirfenidone and Collagen-Polyvinylpyrrolidone on Macroscopic and Microscopic Changes, TGF-<i>β</i>1 Expression, and Collagen Deposition in an Experimental Model of Tracheal Wound Healing

<div>Tracheal wound healing and lumen diameter at the end of the study. (a) Normal wound healing and minimal tracheal lumen decrease in an animal from the SS group. Normal wound healing without stenosis in the group treated with Collagen-PVP (b) and PFD (d). (c) Fibrotic scarring and decreased tracheal lumen in a euthanized animal from group III.</div>

BioMed Research International

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Figure 1

Figure 1: Effects of Pirfenidone and Collagen-Polyvinylpyrrolidone on Macroscopic and Microscopic Changes, TGF-<i>β</i>1 Expression, and Collagen Deposition in an Experimental Model of Tracheal Wound Healing 

Figure 1 | Effects of Pirfenidone and Collagen-Polyvinylpyrrolidone on Macroscopic and Microscopic Changes, TGF-β1 Expression, and Collagen Deposition in an Experimental Model of Tracheal Wound Healing 