Ginsenoside Rg1 Ameliorates Cigarette Smoke-Induced Airway Fibrosis by Suppressing the TGF-β1/Smad Pathway In Vivo and In Vitro

Figure 4

Ginsenoside Rg1 inhibited cigarette smoke extract- (CSE-) induced transdifferentiation of pulmonary fibroblasts. (a) Western blot and quantitative analysis of α-SMA protein expression. (b) Immunocytofluorescence assay of α-SMA (×200 magnification). Scale bar: 200 μm. α-SMA is stained red; nuclei stained with DAPI are blue. Blots are representative of at least four independent experiments. All data are shown as mean ± SD of at least three independent experiments, each performed in triplicate. versus the Sham group; versus the CSE group.

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