Research Article
Multivalent Fusion DNA Vaccine against Brucella abortus
Figure 3
Cytokine levels quantified by ELISA sandwich. Production of (a) IFN-γ and (b) IL-4, present in the supernatant of splenocytes stimulated in vitro with 2 or 10 μg/ml of R273S, R278S, or R273-278S recombinant proteins for 72 h. Results are plotted as mean ± standard deviation. indicates statistically significant values.
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