Can Replacing CA125 with HE4 in Risk of Malignancy Indices 1–4 Improve Diagnostic Performance in the Presurgical Assessment of Adnexal Tumors?

<div>Diagnostic accuracy of classical and modified risk of malignancy indices (RMIs) 1–4 for differentiation of malignant stage I (FIGO) from nonmalignant adnexal masses. Modified RMIs were obtained by replacing cancer antigen 125 with human epididymis secretory protein 4 in the classical RMI. Diagnostic accuracy was based on receiver operating characteristic analysis. Diagonal segments are produced by ties.</div>

BioMed Research International

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Figure 4: Can Replacing CA125 with HE4 in Risk of Malignancy Indices 1–4 Improve Diagnostic Performance in the Presurgical Assessment of Adnexal Tumors? 

Figure 4 | Can Replacing CA125 with HE4 in Risk of Malignancy Indices 1–4 Improve Diagnostic Performance in the Presurgical Assessment of Adnexal Tumors? 