Can Replacing CA125 with HE4 in Risk of Malignancy Indices 1–4 Improve Diagnostic Performance in the Presurgical Assessment of Adnexal Tumors?

Table 4

Distribution of age, menopause, ultrasound score, and maximum tumor diameter in patients with adnexal mass.

Parameter	Nonmalignant	Malignant	value
Age, years
<30	42 (16.2%)	1 (1.9%)	<0.001
31–40	68 (26.2%)	3 (5.8%)
41–50	60 (23.1%)	7 (13.5%)
>50	90 (34.6%)	41 (78.8%)
Menopausal status
Premenopausal	184 (70.8%)	11 (21.2%)	<0.001
Postmenopausal	76 (29.2%)	41 (78.8%)
Ultrasound score
≤1	227 (87.3%)	15 (28.8%)	<0.001
2–5	33 (12.7%)	37 (71.2%)
Maximum tumor diameter
<70 mm	169 (65.0%)	15 (28.8%)	<0.001
≥70 mm	91 (35.0%)	37 (71.2%)

Data are shown as numbers and frequencies (percentage). values were computed using the chi-square test.