The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2

Figure 2

Analyses of MMP2 and miR-29b-3p expression in the vitamin D3 group and the control group. (a) Western blot analyses for MMP2 protein in rat aortas from the control group (C1, C2, and C3) and the vitamin D3-treated group (M1, M2, and M3). (b) Scatter diagram for expression of MMP2 and miR-29b-3p. MMP2 expression was significantly increased and miR-29b-3p was significantly downregulated in the vitamin D3 group. (c, d) Correlation analyses to determine the relationships between miR-29b-3p and MMP2 mRNA levels and MMP2 protein in the control and vitamin D3 groups (MMP2 mRNA versus miR-29b-3p, , ; MMP2 protein versus miR-29b-3p, , ).

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