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BioMed Research International
Volume 2017 (2017), Article ID 6759810, 13 pages
Research Article

The Response of Macro- and Micronutrient Nutrient Status and Biochemical Processes in Rats Fed on a Diet with Selenium-Enriched Defatted Rapeseed and/or Vitamin E Supplementation

1Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences in Prague, Prague, Czech Republic
2Institute of Physiology, Academy of Science of the Czech Republic, Prague, Czech Republic
3Faculty of Chemical Engineering, University of Chemistry and Technology, Prague, Czech Republic
4Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czech Republic

Correspondence should be addressed to Jiřina Száková

Received 6 February 2017; Revised 30 March 2017; Accepted 7 May 2017; Published 30 May 2017

Academic Editor: Swaran J. S. Flora

Copyright © 2017 Michaela Rýdlová et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The response of nutrient status and biochemical processes in (i) Wistar and (ii) spontaneously hypertensive (SHR) rats upon dietary intake of selenium- (Se-) enriched defatted rapeseed (DRS) and/or vitamin E fortification was examined to assess the health benefit of DRS in animal nutrition. Twenty-four individuals of each type of rat were used: The control group was fed with an untreated diet (Diet A). In Diets B and C, soybean meal was replaced with defatted DRS, which comprised 14% of the total diet. The selenized DRS application resulted in ~3-fold increase of Se content in the diet. Diet C was also fortified with the addition of vitamin E, increasing the natural content by 30%. The Se content of the blood and kidneys tended to increase in the DRS groups, where the changes were significant () only in the case of SHR rats. The iodine (I) content and the proportion of iodide in rat livers indicated a lower transformation rate of iodide into organoiodine compounds compared to the control. Slight and ambiguous alterations in the antioxidative response of the rat were observed in the DRS groups, but the addition of vitamin E to the diet helped to moderate these effects.