Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study
Table 4
Associations between possible risk factors and CS. Values are expressed as odds ratio (OR) with corresponding 95% confidence intervals (CI). (1 missing).
Risk factors for CS during delivery
CS/total (%)
OR unadjusted (95% CI)
OR adjusted (95% CI)
Maternal age
<30 years
161/856 (19)
Ref.
Ref.
30
677/3091 (22)
1.2 (1.0–1.5)
1.5 (1.2–1.8)
Parity
Multiparos
225/1639 (14)
Ref.
Ref.
Primiparous
628/2364 (27)
2.3 (1.9–2.7)
2.4 (2.0–2.8)
Gestational age (days)
<41 + 0
344/2072 (17)
Ref.
Ref.
41 + 0
485/1824 (27)
1.8 (1.5–2.1)
1.9 (1.5–2.3)
Indication for induction
(i) PROM
147/881 (17)
Ref.
Ref.
(ii) Postdate
269/1090 (25)
1.6 (1.3–2.0)
1.7 (1.3–2.2)
(iii) Maternal (>41 w)
197/712 (28)
1.9 (1.5–2.4)
1.8 (1.4–2.4)
(iv) Fetal
91/434 (21)
1.3 (1.0–1.8)
1.5 (1.1–2.0)
(v) Nonmedical
148/885 (17)
1.0 (0.8–1.3)
1.3 (0.96–1.7)
Years of induction
(i) 2012-2013
358/2085 (17)
Ref
Ref
(ii) 2009-2010
495/1918 (26)
1.7 (1.4–2.0)
1.5 (1.0–2.0)
Bishop score
>5
167 (1123) (15)
Ref.
Ref.
≤5
661/2780 (24)
1.7 (1.5–2.1)
1.2 (0.94–1.6)
Method of induction
(i) Misoprostol
308/1675 (18)
Ref.
Ref.
(ii) Dinoproston
291/933 (31)
2.0 (1.7–2.4)
1.4 (0.96–2.1)
(iii) Amniotomy
106/753 (14)
0.7 (0.6–0.9)
0.8 (0.5–1.2)
(iv) Balloon catheter
82/333 (25)
1.4 (1.1–1.9)
1.2 (0.8–1.9)
(v) Oxytocin
28/228 (12)
0.6 (0.4–0.9)
0.8 (0.5–1.3)
(vi) Dinoproston
38/81 (47)
3.9 (2.5–6.2)
2.9 (1.6–5.2)
,, and values < 0.05 were considered as statistically significant.