Research Article

Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study

Table 4

Associations between possible risk factors and CS. Values are expressed as odds ratio (OR) with corresponding 95% confidence intervals (CI). (1 missing).

Risk factors for CS during deliveryCS/total (%)OR unadjusted
(95% CI)
OR adjusted
(95% CI)

Maternal age
 <30 years161/856 (19)Ref.Ref.
30677/3091 (22)1.2 (1.0–1.5)1.5 (1.2–1.8)
Parity
 Multiparos225/1639 (14)Ref.Ref.
 Primiparous628/2364 (27)2.3 (1.9–2.7)2.4 (2.0–2.8)
Gestational age (days)
 <41 + 0344/2072 (17)Ref.Ref.
41 + 0485/1824 (27)1.8 (1.5–2.1)1.9 (1.5–2.3)
Indication for induction
 (i) PROM147/881 (17)Ref.Ref.
 (ii) Postdate269/1090 (25)1.6 (1.3–2.0)1.7 (1.3–2.2)
 (iii) Maternal (>41 w)197/712 (28)1.9 (1.5–2.4)1.8 (1.4–2.4)
 (iv) Fetal91/434 (21)1.3 (1.0–1.8)1.5 (1.1–2.0)
 (v) Nonmedical148/885 (17)1.0 (0.8–1.3)1.3 (0.96–1.7)
Years of induction
 (i) 2012-2013358/2085 (17)RefRef
 (ii) 2009-2010495/1918 (26)1.7 (1.4–2.0)1.5 (1.0–2.0)
Bishop score
 >5167 (1123) (15) Ref.Ref.
 ≤5661/2780 (24)1.7 (1.5–2.1)1.2 (0.94–1.6)
Method of induction
 (i) Misoprostol308/1675 (18)Ref.Ref.
 (ii) Dinoproston291/933 (31)2.0 (1.7–2.4)1.4 (0.96–2.1) 
 (iii) Amniotomy106/753 (14)0.7 (0.6–0.9)0.8 (0.5–1.2)
 (iv) Balloon catheter82/333 (25)1.4 (1.1–1.9)1.2 (0.8–1.9)
 (v) Oxytocin28/228 (12)0.6 (0.4–0.9)0.8 (0.5–1.3)
 (vi) Dinoproston38/81 (47)3.9 (2.5–6.2)2.9 (1.6–5.2)

, , and values < 0.05 were considered as statistically significant.