Clinical Study

A Randomized Controlled Trial Evaluating the Effects of Diosmin in the Treatment of Radicular Pain

Table 1

Baseline characteristics of the patients.

Diosmin group
Control group
value

Male (, %)76, 50.7%73, 48.7%0.729
Age (years, mean ± SD)41 ± 6.542 ± 7.40.215
Treatment course (months, mean ± SD)4 ± 1.44 ± 1.51.000
Duration of pain (, %)
 <3 months45, 30.0%47, 31.3%0.909
 3–12 months62, 41.3%65, 65%
 13–36 months29, 19.3%27, 18.0%
 >36 months14, 9.3%11, 7.3%
Pretreatment with opioids (, %)
 None118, 78.5%114, 76.0%0.849
 <60 morphine equivalents/day21, 14.0%23, 15.3%
 ≥60 morphine equivalents/day11, 7.3%13, 8.7%
Current smoker (, %)21, 14.0%23, 15.3%0.744
Obesity (, %)23, 15.3%25, 16.7%0.753
Level of lesion (culprit nerve root, , %)
 L2-3/L39, 6.0%11, 7.3%0.788
 L3-4/L413, 8.7%15, 10.0%
 L4-5/L599, 66.0%101, 67.3%
 L5-S1/S129, 19.3%23, 15.3%
Baseline pain scores (mean ± SD)
 VAS89 ± 1191 ± 40.037
 RM-Q17.2 ± 2.717.4 ± 2.30.490
 NRS7.8 ± 0.77.8 ± 0.30.222
Number of patients with serious pain given diclofenac (, %)6, 3.9%5, 3.3%0.759

SD, standard deviation; VAS, visual analog scale; RM-Q, Roland-Morris Questionnaire; NRS, numerical rating scale.