Impact of Elevated Circulating Histones on Systemic Inflammation after Radiofrequency Ablation in Lung Cancer Patients

Figure 4

Stimulatory effects of lung cancer patients’ serum on human monocytic cells. There were 6 histone-related cytokines significantly increased in the supernatant of post-RFA lung cancer patients’ sera-treated human monocytic U937 cells, whereas addition of anti-histone H4 antibody decreased most cytokine levels. Variables were expressed as mean ± standard deviation (SD).