Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2017 (2017), Article ID 6894832, 6 pages
https://doi.org/10.1155/2017/6894832
Research Article

Impact of Elevated Circulating Histones on Systemic Inflammation after Radiofrequency Ablation in Lung Cancer Patients

1Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
2Department of Oncology, First Hospital of Qinhuangdao, Qinhuangdao, Hebei 066000, China
3Medical Research Center, Beijing Chao-Yang Hospital, Beijing 100020, China

Correspondence should be addressed to Zhiyong Yuan; nc.anis@6102nauyrd

Received 28 July 2017; Accepted 26 November 2017; Published 31 December 2017

Academic Editor: Xin-yuan Guan

Copyright © 2017 Tao Gu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. Chen, R. Zheng, P. D. Baade et al., “Cancer statistics in China, 2015,” CA: A Cancer Journal for Clinicians, vol. 66, no. 2, pp. 115–132, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Wen, L. Gao, Z. Wen et al., “Exploratory investigation of plasma metabolomics in human lung adenocarcinoma,” Molecular BioSystems, vol. 9, no. 9, pp. 2370–2378, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Hiraki, H. Gobara, T. Iguchi, H. Fujiwara, Y. Matsui, and S. Kanazawa, “Radiofrequency ablation for early-stage nonsmall cell lung cancer,” BioMed Research International, vol. 2014, Article ID 152087, 11 pages, 2014. View at Publisher · View at Google Scholar
  4. H. Takaki, N. Imai, C. T. Thomas et al., “Changes in peripheral blood T-cell balance after percutaneous tumor ablation,” Minimally Invasive Therapy & Allied Technologies, vol. 26, no. 6, pp. 331–337, 2017. View at Publisher · View at Google Scholar
  5. J. Wan, W. Wu, Y. Huang, W. Ge, and S. Liu, “Incomplete radiofrequency ablation accelerates proliferation and angiogenesis of residual lung carcinomas via HSP70/HIF-1α,” Oncology Reports, vol. 36, no. 2, pp. 659–668, 2016. View at Publisher · View at Google Scholar · View at Scopus
  6. B. Liu, L. Liu, M. Hu, K. Qian, and Y. Li, “Effect of percutaneous radiofrequency ablation after thoracoscopic pleurodesis for treating non-small cell lung cancer patients with malignant pleural effusion and/or pleural dissemination,” Thoracic Cancer, vol. 7, no. 5, pp. 549–555, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. M. C. Jansen, S. van Wanrooy, R. van Hillegersberg et al., “Assessment of systemic inflammatory response (SIR) in patients undergoing radiofrequency ablation or partial liver resection for liver tumors,” European Journal of Surgical Oncology, vol. 34, no. 6, pp. 662–667, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Chen, R. Kang, X. Fan, and D. Tang, “Release and activity of histone in diseases,” Cell Death & Disease, vol. 5, no. 8, Article ID e1370, 2014. View at Publisher · View at Google Scholar
  9. X. Lv and H. Wang, “Pathophysiology of sepsis-induced myocardial dysfunction,” Military Medical Research, vol. 3, no. 1, article 30, 2016. View at Publisher · View at Google Scholar · View at Scopus
  10. S. T. Abrams, N. Zhang, J. Manson et al., “Circulating histones are mediators of trauma-associated lung injury,” American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 2, pp. 160–169, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Chaput and A. Zychlinsky, “Sepsis: the dark side of histones,” Nature Medicine, vol. 15, no. 11, pp. 1245-1246, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. T. A. Fuchs, A. A. Bhandari, and D. D. Wagner, “Histones induce rapid and profound thrombocytopenia in mice,” Blood, vol. 118, no. 13, pp. 3708–3714, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. F. Semeraro, C. T. Ammollo, J. H. Morrissey et al., “Extracellular histones promote thrombin generation through platelet-dependent mechanisms: Involvement of platelet TLR2 and TLR4,” Blood, vol. 118, no. 7, pp. 1952–1961, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Yamamichi, Y. Fujiwara, T. Kikuchi, M. Nishitani, Y. Matsushita, and K. Hasumi, “Extracellular histone induces plasma hyaluronan-binding protein (factor VII activating protease) activation in vivo,” Biochemical and Biophysical Research Communications, vol. 409, no. 3, pp. 483–488, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. C. T. Ammollo, F. Semeraro, J. Xu, N. L. Esmon, and C. T. Esmon, “Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation,” Journal of Thrombosis and Haemostasis, vol. 9, no. 9, pp. 1795–1803, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Hoeksema, M. Van Eijk, H. P. Haagsman, and K. L. Hartshorn, “Histones as mediators of host defense, inflammation and thrombosis,” Future Microbiology, vol. 11, no. 3, pp. 441–453, 2016. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Daigo, Y. Takamatsu, and T. Hamakubo, “The protective effect against extracellular histones afforded by long-pentraxin PTX3 as a regulator of NETs,” Frontiers in Immunology, vol. 7, article 344, pp. 1–9, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. K. C. A. A. Wildhagen, P. G. de Frutos, C. P. Reutelingsperger et al., “Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis,” Blood, vol. 123, no. 7, pp. 1098–1101, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. Z. Wen, Z. Lei, L. Yao et al., “Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure,” Cell Death & Disease, vol. 7, no. 9, article e2391, 2016. View at Publisher · View at Google Scholar
  20. A. Stang, M. Donati, H. Weilert, and K. J. Oldhafer, “Impact of systemic therapy and recurrence pattern on survival outcome after radiofrequency ablation for colorectal liver metastases,” Journal of Cancer, vol. 7, no. 14, pp. 1939–1949, 2016. View at Publisher · View at Google Scholar · View at Scopus
  21. O. Akhan, E. Guler, D. Akinci, T. Ciftci, and I. C. Kose, “Radiofrequency ablation for lung tumors: outcomes, effects on survival, and prognostic factors,” Diagnostic and Interventional Radiology, vol. 22, no. 1, pp. 65–71, 2015. View at Publisher · View at Google Scholar
  22. T. Gu, Y. Ge, Y. Song et al., “Hepatic radiofrequency ablation causes an increase of circulating histones in patients with hepatocellular carcinoma,” Scandinavian Journal of Clinical & Laboratory Investigation, vol. 75, no. 7, pp. 621–627, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Schneider, A. Sevko, C. Heussel et al., “Serum inflammatory factors and circulating immunosuppressive cells are predictive markers for efficacy of radiofrequency ablation in non-small cell lung cancer,” Clinical & Experimental Immunology, vol. 180, no. 3, pp. 467–474, 2015. View at Publisher · View at Google Scholar
  24. R. Allam, S. V. R. Kumar, M. N. Darisipudi, and H.-J. Anders, “Extracellular histones in tissue injury and inflammation,” Journal of Molecular Medicine, vol. 92, no. 5, pp. 465–472, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Xu, X. Zhang, R. Pelayo et al., “Extracellular histones are major mediators of death in sepsis,” Nature Medicine, vol. 15, no. 11, pp. 1318–1321, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. X. Lv, T. Wen, J. Song et al., “Extracellular histones are clinically relevant mediators in the pathogenesis of acute respiratory distress syndrome,” Respiratory Research, vol. 18, no. 1, p. 165, 2017. View at Publisher · View at Google Scholar
  27. J. P. Erinjeri, C. T. Thomas, A. Samoilia et al., “Image-guided thermal ablation of tumors increases the plasma level of interleukin-6 and interleukin-10,” Journal of Vascular and Interventional Radiology, vol. 24, no. 8, pp. 1105–1112, 2013. View at Publisher · View at Google Scholar · View at Scopus