Investigation into Hypoglycemic, Antihyperlipidemic, and Renoprotective Potentials of Dennettia tripetala (Pepper Fruit) Seed in a Rat Model of Diabetes
Table 4
Atherogenic index and percentage protection of CMEDT and MFDT.
Group
Treatment (twice daily)
Changes in serum lipid profile in mg/dl
Atherogenic index (AI)
% protection
T. chol.
HDL
A
CMEDT 50 mg/kg body weight
2.97
22.01
B
CMEDT 100 mg/kg body weight
2.33
38.85
C
MFDT 50 mg/kg body weight
3.36
11.81
D
MFDT 100 mg/kg body weight
2.15
43.57
E
Glibenclamide 10 mg/kg body weight (positive control)
2.19
42.52
F
Negative (untreated) control
3.81
0
G
Normal control
1.98
48.03
Values are mean ± SEM; ; % protection as compared to untreated control group.