The Efficacy of Single-Dose versus Double-Dose Praziquantel Treatments on Schistosoma mansoni Infections: Its Implication on Undernutrition and Anaemia among Primary Schoolchildren in Two On-Shore Communities, Northwestern Tanzania

Table 2

Cure rates of PZQ 40 mg/kg stratified by demographic characteristics and baseline infection intensity.

Characteristic	Treatment regimen
	Single dose		Double dose		value
	Treated ()	Cured (%(95% CI))	Treated ()	Cured (%(95% CI))
Overall	182	125 (68.68 (61.90–75.46))	174	162 (93.10 (89.31–96.89))	<0.001
Sex
Male	89	66 (74.16 (64.94–83.69))	81	78 (96.30 (92.13–100))	<0.001
Female	93	59 (63.44 (53.54–73.35))	93	84 (90.32 (84.24–96.40))	<0.001
Village
Kibuyi	96	61 (63.54 (53.80–73.28))	85	82 (96.47 (92.49–100))	<0.001
Busanga	86	64 (74.42 (65.08–83.76))	89	80 (89.89 (83.54–96.23))	0.007
Age (years)
6–9	38	19 (50.00 (33.63–66.37))	39	38 (97.44 (92.33–100))	<0.001
10–12	84	60 (71.43 (61.64–81.22))	87	81 (93.10 (87.71–98.49))	<0.001
13–16	60	46 (76.67 (65.75–87.58))	48	43 (89.58 (80.75–98.41))	0.080
Intensity
Light	64	47 (73.44 (62.41–84.46))	49	46 (93.88 (87.02–100))	0.005
Moderate	86	57 (66.28 (56.15–76.41))	66	63 (95.45 (90.35–100))	<0.001
Heavy	32	21 (65.63 (48.68–82.57))	59	53 (89.83 (81.95–97.72))	0.005

values are based on chi-square statistic.