Long Noncoding RNA PVT1 as a Novel Diagnostic Biomarker and Therapeutic Target for Melanoma

Figure 1

PVT1 expression levels in melanoma. (a) PVT1 expression levels in melanoma tissues and nonneoplastic nevi tissues using Oncomine expression analysis (Haqq et al., 2005). by Mann–Whitney test. (b) PVT1 expression levels in normal skin, benign and atypical nevi, melanoma in suit, and melanoma tissues using Oncomine expression analysis (Smith et al., 2005; GSE4587). (c) PVT1 expression levels in 30 malignant melanoma tissues and 20 age and gender-matched skin tissues were measured by qPCR. by Mann–Whitney test. (d) PVT1 expression levels in 30 melanoma tissues with different clinical stages were measured by qPCR. by Mann–Whitney test.

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