Ameliorating Effect of Gemigliptin on Renal Injury in Murine Adriamycin-Induced Nephropathy

Figure 5

Effects of gemigliptin on adriamycin-induced podocyte loss (a); immunofluorescence stain for WT-1 (red) and DAPI (blue) and double-positive cells (pink) (b); mean podocyte number per glomerulus in each group is presented and shown for DAPI-positive and WT-1 positive cells; the asterisk indicates that the difference in mean podocyte number per glomerulus between groups is significant. p values are obtained using the one-way analysis of variance test followed by Tukey’s post hoc test. compared with (A), compared with (B), and compared with (C). GM, gemigliptin; ADR, adriamycin; WT-1, Wilms tumor-1; DAPI, 4′,6-diamidino-2-phenylindole.

(a)

(b) WT-1/Glomerulus