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BioMed Research International
Volume 2017, Article ID 7320859, 6 pages
https://doi.org/10.1155/2017/7320859
Research Article

The Clinical Significance of FilmArray Respiratory Panel in Diagnosing Community-Acquired Pneumonia

1Cell Biology and Genetics Department, Shantou University Medical College, Shantou 515041, China
2First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China

Correspondence should be addressed to Changwen Ke; moc.nuyila@5691wcek and Xiaoyang Jiao; nc.ude.uts@oaijyx

Received 10 May 2017; Accepted 11 July 2017; Published 6 September 2017

Academic Editor: Graciela Russomando

Copyright © 2017 Huanzhu Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim. FilmArray Respiratory Panel (FilmArray RP) test is an emerging diagnostic method in fast detecting multiple respiratory pathogens; the methodology and clinical significance of FilmArray RP in community-acquired pneumonia (CAP) diagnosis were evaluated in this study. Methods. Specimens from 74 patients with CAP were analyzed and compared using FilmArray RP, traditional multiple PCR assay, bacterial (or fungal) culture, and serological detection. Results. FilmArray RP and multiplex PCR showed 100% coincidence rate in detecting coronaviruses 229E, OC43, HKU1, and NL63, human metapneumovirus, influenza A and B, and parainfluenza viruses (PIV1, PIV2, and PIV4). There were 15 viral specimens tested as disagreement positive results. FilmArray RP had higher detection rate in detecting dual viral and Mycoplasma pneumoniae infection. The positive bacteria (or fungi) were found in 25 specimens. Conclusions. This study demonstrated the capability of FilmArray RP for simultaneous detection of broad-spectrum respiratory pathogens and potential use in facilitating better patient care.