Vitamin B-6, Independent of Homocysteine, Is a Significant Factor in Relation to Inflammatory Responses for Chronic Kidney Disease and Hemodialysis Patients

Table 3

Partial Spearman’s correlation coefficients () of vitamin B-6 and homocysteine with inflammatory markers in all patients.

Parameters	(no additionally adjusted homocysteine)			(additionally adjusted homocysteine)
	PLP; (nmol/L)	PL; (nmol/L)	PLP + PL; (nmol/L)	PLP; (nmol/L)	PL; (nmol/L)	PLP + PL; (nmol/L)
CRP (mg/L)	−0.22	—	−0.21	−0.22	—	−0.22
Interleukin-1 (pg/mL)	—^1	—	0.22	—	—	0.22
Interleukin-4 (pg/mL)	—	—	—	—	—	—
Interleukin-6 (pg/mL)	—	—	—	—	—	—
Interleukin-8 (pg/mL)	—	—	—	—	—	—
Interleukin-10 (pg/mL)	—	−0.21	—	—	−0.23	—
TNF- (pg/mL)	—	—	—	—	—	—

= 136. Values are partial correlation coefficient (). . Adjusting for age, gender, body mass index, systolic blood pressure, serum albumin, diabetes, chronic kidney disease stage, plasma homocysteine, B-vitamin supplement usage, smoking and drinking habits; PLP, pyridoxal 5′-phosphate; PL, pyridoxal; CRP, C-reactive protein; TNF-, tumor necrosis factor-; No significance.