Apoptotic Signaling Pathways in Glioblastoma and Therapeutic Implications

Figure 2

miRNAs in GSC Apoptosis. Schematic representation of the interactions between miRNAs and apoptosis signals in GSCs. Red lines represent the findings discussed in text (solid lines for direct and dashed lines for indirect regulation) while black lines represent established apoptotic pathways. Framed miRNAs or proteins indicate whether they are overexpressed (red frame) or underexpressed (blue frame) in GSCs.