Variety of RNAs in Peripheral Blood Cells, Plasma, and Plasma Fractions

Figure 1

Analysis of intrinsic characteristics of human blood plasma (II) and plasma fractions: particles, pelleted at 16,000 (III) and 160,000 (IV) and vesicle-depleted plasma (V). ((a) and (b)) TEM analysis of ultrathin sections of fractions III and IV. Black arrows indicate membrane vesicles, white arrows indicate macromolecular aggregates and cell debris, and asterisks indicate mitochondria; (c) DLS analysis of blood fractions II–V; (d) comparative analysis of CD41a+ and CD3+ particle distribution between fractions III and IV of healthy donors and patients with non-small cell lung cancer (NSCLC); (e) flow cytometry assessment of CD63+ particles in fractions III and IV. .

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