Association between Parathyroid Hormone, 25 (OH) Vitamin D, and Chronic Kidney Disease: A Population-Based Study
Table 3
OR of variables associated with eGFR less than 60 mL/min.
Variable
Crude
Model 1
Model 2
OR (95% CI)
OR (95% CI)
OR (95% CI)
Continuous variables
25 (OH) vitamin D, ug/mL
1.023 (1.015–1.031)
<0.001
1.001 (0.992–1.010)
0.795
1.005 (0.996–1.015
0.276
Log intact PTH, pmol/L
1.985 (1.663–2.371)
<0.001
1.618 (1.345–1.948)
<0.001
1.796 (1.479–2.181
<0.001
Calcium, mg/dL
1.276 (1.020–1.597)
0.033
1.475 (1.168–1.862)
0.001
1.617 (1.270–2.060
<0.001
Phosphate, mg/dL
0.802 (0.694–0.926)
0.003
1.086 (0.919–1.283)
0.332
1.138 (0.959–1.350
0.137
Categorical variables
Vitamin D sufficient (yes versus no)
1
1
1
Vitamin D deficient (yes versus no)
0.642 (0.544–0.758)
<0.001
0.872 (0.662–1.149)
0.330
0.959 (0.725–1.269
0.771
Vitamin D insufficient (yes versus no)
0.623 (0.485–0.800)
<0.001
0.726 (0.558–0.944)
0.017
0.777 (0.595–1.014
0.063
Hyperparathyroidism (yes versus no)
2.530 (2.057–3.112)
<0.001
2.074 (1.662–2.589)
<0.001
2.128 (1.699–2.667
<0.001
Hypocalcemia (yes versus no)
1.236 (0.529–2.892)
0.624
0.940 (0.374–2.360)
0.896
0.659 (0.261–1.665
0.378
Hyperphosphatemia (yes versus no)
0.935 (0.728–1.200)
0.598
1.237 (0.948–1.612)
0.117
1.298 (0.994–1.696
0.560
OR: odd ratios; CI: confidence interval. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, and all other continuous variables; adjusted for age, gender, and all other categorical variables.
