Association between Parathyroid Hormone, 25 (OH) Vitamin D, and Chronic Kidney Disease: A Population-Based Study
Table 4
OR of variables associated with proteinuria.
Variable
Crude
Model 1
Model 2
OR (95% CI)
p
OR (95% CI)
p
OR (95% CI)
p
Continuous variables
25 (OH) vitamin D, ug/mL
1.016 (1.008–1.025)
<0.001
1.000 (0.991–1.010)
0.941
1.004 (0.994–1.014
0.457
Log intact PTH, pmol/L
1.744 (1.442–2.109)
<0.001
1.477 (1.217–1.793)
<0.001
1.579 (1.291–1.932
<0.001
Calcium, mg/dL
1.159 (0.907–1.481)
0.237
1.252 (0.980–1.599)
0.072
1.330 (1.037–1.705
0.025
Phosphate, mg/dL
0.865 (0.740–1.012)
0.069
1.070 (0.897–1.276)
0.452
1.118 (0.935–1.338
0.222
Categorical variables
Vitamin D sufficient (yes versus no)
1
1
1
Vitamin D deficient (yes versus no)
1.386 (1.060–1.813)
0.017
0.887 (0.666–1.183)
0.416
0.963 (0.720–1.289
0.801
Vitamin D insufficient (yes versus no)
0.971 (0.747–1.263)
0.826
0.756 (0.576–0.992)
0.044
0.802 (0.609–1.056
0.115
Hyperparathyroidism (yes versus no)
2.212 (1.770–2.766)
<0.001
1.865 (1.480–2.351)
<0.001
1.895 (1.497–2.398
<0.001
Hypocalcemia (yes versus no)
1.332 (0.542–3.272)
0.532
1.109 (0.436–2.821)
0.827
0.821 (0.320–2.107
0.682
Hyperphosphatemia (yes versus no)
0.992 (0.759–1.298)
0.955
1.201 (0.909–1.587)
0.198
1.249 (0.943–1.653
0.120
OR: odd ratios; CI: confidence interval. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, and all other continuous variables; adjusted for age, gender, and all other categorical variables.
